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Dr Christian Pflueger

  • Research Associate, The University Of Western Australia
  • group: lister

Research:

Epigenetic Engineering

Contact Info:

Year Publication Online
2024
Khan MA, Herring G, Zhu JY, Oliva M, Fourie E, Johnston B, Zhang Z, Potter J, Pineda L, Pflueger J, Swain T, Pflueger C, Lloyd JPB, Secco D, Small I, Kidd BN, Lister R (2024) CRISPRi-based circuits to control gene expression in plants. Nat Biotechnol (in press).
NCBI Pubmed DOI Link
2024
Swain T, Pflueger C, Freytag S, Poppe D, Pflueger J, Nguyen TV, Li JK, Lister R (2024) A modular dCas9-based recruitment platform for combinatorial epigenome editing. Nucleic Acids Res 52(1):474-491.
NCBI Pubmed DOI Link
2022
Lloyd JPB, Ly F, Gong P, Pflueger J, Swain T, Pflueger C, Fourie E, Khan MA, Kidd BN, Lister R (2022) Synthetic memory circuits for stable cell reprogramming in plants. Nat Biotechnol 40(12):1862-1872.
NCBI Pubmed DOI Link
2022
Herring CA, Simmons RK, Freytag S, Poppe D, Moffet JJD, Pflueger J, Buckberry S, Vargas-Landin DB, Clément O, Echeverría EG, Sutton GJ, Alvarez-Franco A, Hou R, Pflueger C, Mcdonald K, Polo JM, Forrest ARR, Nowak AK, Voineagu I, Martelotto L, Lister R (2022) Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution. Cell 185(23):4428-4447.e28.
NCBI Pubmed DOI Link
2019
Diefenbach RJ, Lee JH, Chandler D, Wang Y, Pflueger C, Long GV, Scolyer RA, Carlino MS, Menzies AM, Kefford RF, Rizos H (2019) Hypermethylation of Circulating Free DNA in Cutaneous Melanoma APPLIED SCIENCES 9(23):5074.
DOI Link
2019
Pflueger C, Swain T, Lister R (2019) Harnessing targeted DNA methylation and demethylation using dCas9. ESSAYS BIOCHEM. 63(6):813-825.
NCBI Pubmed DOI Link
2018
Pflueger C, Tan D, Swain T, Nguyen T, Pflueger J, Nefzger C, Polo JM, Ford E, Lister R (2018) A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs. GENOME RES 28(8):1193-1206.
NCBI Pubmed DOI Link
2017
Hendrickson PG, Doráis JA, Grow EJ, Whiddon JL, Lim JW, Wike CL, Weaver BD, Pflueger C, Emery BR, Wilcox AL, Nix DA, Peterson CM, Tapscott SJ, Carrell DT, Cairns BR (2017) Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons. NAT GENET 49(6):925-934.
NCBI Pubmed DOI Link
2016
Ramakrishnan S, Pokhrel S, Palani S, Pflueger C, Parnell TJ, Cairns BR, Bhaskara S, Chandrasekharan MB (2016) Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription. NAT COMMUN 7:11949.
NCBI Pubmed DOI Link
2015
Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB (2015) Interaction of the Jhd2 H3K4 demethylase with chromatin is controlled by histone H2A surfaces and restricted by H2B ubiquitination J BIOL CHEM 290(48):28760-77.
NCBI Pubmed DOI Link
2014
Jenkins TG, Aston KI, Pflueger C, Cairns BR, Carrell DT (2014) Age-associated sperm DNA methylation alterations: possible implications in offspring disease susceptibility PLOS GENET 10(7):e1004458.
NCBI Pubmed DOI Link
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